The death rate was three patients in the ivermectin group (3.7%) versus four patients (4.9%) in the control group without any significant difference between the two groups (p = 1.00). Three patients (3.7%) in each group required mechanical ventilation (p = 1.00). Patients in the ivermectin group had a shorter length of hospital stay (8.82 ± 4.94 days) than the control group (10.97 ± 5.28 days), but this was not statistically significant (p = 0.085). Overall, 82 individuals were randomized to receive ivermectin plus standard of care and 82 to receive standard of care alone. All patients were followed up for 1 month. The main outcomes were mortality, the length of hospital stay, and the need for mechanical ventilation. Patients were randomized into two groups where Group 1 (Ivermectin group) included patients who received ivermectin 12 mg once daily for 3 days with standard care and Group 2 (control group) included patients who received standard protocol of treatment alone for 14 days. This was a randomized open-label controlled study that included 164 patients with COVID-19. This study aimed to evaluate the efficacy of ivermectin for the treatment of hospitalized mild to moderate COVID-19 infected patients. Researchers around the world are working at record speed to find the best ways to treat and prevent coronavirus disease 2019 (COVID-19). 9 Department of Endemic Medicine, Kasr Alainy School of Medicine, Cairo University, Cairo, Egypt.8 Department of Internal Medicine, Al-Azhar University, Cairo, Egypt.7 Department of Microbiology and Immunology, Tanta University, Tanta, Egypt.6 Department of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assiut University, Assiut, Egypt.5 Department of Emergency Medicine and traumatology, Faculty of Medicine, Tanta University, Tanta, Egypt.4 Department of Anesthesia, Surgical Intensive Care, and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.3 Department of Public health and Community Medicine, Faculty of Medicine, Menoufia University, Menoufia, Egypt. ![]() 2 Department of Internal Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.1 Department of Tropical Medicine and Infectious diseases, Faculty of Medicine, Tanta University, Tanta, Egypt.
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